Studies of peptide folding

A collaborative project with the Dyer lab

at Los Alamos National Laboratory

9/11/2002


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Table of Contents

Studies of peptide folding

b-sheet vs. a-helix folding

b-sheet folding followed by T-jump methods

GB1 b-sheet folding occurs in 3.5 ms

Cyclic b-sheet forming peptides

Folding properties of cyclic b-sheet forming peptides

Protein folding studied by infrared temperature jump transient absorption

Spectral Analysis

Spectral Analysis of the hexamer

Spectral Analysis of the decamer

Spectral Analysis of the 14-mer

PPT Slide

Melting curves

Experiment and theory

Quench dynamics predict unfolded structure

Experiment and theory

Kinetics

Arrhenius plots provide activation enthalpy

Author: Stefan Franzen

Email: Stefan_Franzen@ncsu.edu

Home Page: http://chsfpc5.chem.ncsu.edu/sf.html